赵国屏：男，1948年出生。分子微生物学家。1982年毕业于复旦大学生物系微生物学专业，获科学学士学位。1983年，作为CUSBEA研究生赴美国普度大学生物化学系学习，1990年获博士学位。2005年，当选为中国科学院院士。先后获国家自然科学二等奖、国家科技进步二等奖、何梁何利科技进步奖以及省部级奖多项。

中国科学院上海生命科学研究院植物生理生态研究所研究员，国家人类基因组南方研究中心执行主任，生物芯片上海国家工程研究中心主任，复旦大学生命学院微生物与微生物工程系主任（兼职），香港中文大学医学院微生物系讲座教授（兼职）。中国微生物学会理事长、中国生物工程学会理事，上海生物工程学会理事长，上海市科协委员、浦东新区科协副主席。

长期从事微生物生理生化、代谢调控及酶作用机理的研究[1、2]。领导建立基因组和功能基因组学研究平台[3]，参与人类疾病基因组[4、5]和家蚕基因组[6]工作。启动中国微生物基因组测序工作并主持若干重要微生物的基因组和功能基因组研究[7、8、9、10、11、12、13]。近年来，开创微生物代谢酶乙酰化调控研究领域[14]，整合分子遗传学、代谢组、蛋白质组与结构生物学的技术与知识，开展微生物系统生物学和合成生物学研究。目前，主要从事放线菌分子生理和病理[15]以及微生物泛基因组与元基因组[16]的研究和开发工作。

Selected Publication

1. Yang, Y.L., W.H. Jiang, J.S. Chiao, and G.P. Zhao* (1998). Regulation of rifamycin SV production and glutamine synthetase expression in Amycolatopsis mediterranei U-32. Actinomycetol. 12: 141-147

2. Xi Huang, et al., Guoping Zhao* (2002). Affinity alkylation of the Trp-B4 residue of the β-subunit of the glutaryl 7-aminocephalosporanic acid acylase of Pseudomonas sp.l30. J Bio Chem 277: 10256-10264

3. Ze-Guang Han, Guo-Ping Zhao and Zhu Chen (2003). Transcriptome study in China. C. R. Biologies 326: 949-957

4. Xiao S, et al., Zhao G, Kong X* (2001). Dentinogenesis imperfecta 1 with or without progressive hearing loss is associated with distinct mutations in DSPP. Nat Genet 27: 201-204

5. Bu L, et al., Zho G. Hayden MR, Kong X* (2002). Mutant DNA-binding domain of HSF4 is associated with autosomal dominant lamellar and Marner cataract. Nat Genet 31: 276-278

6. Xue-Xia Miao, et al., Guo-Ping Zhao*, Yong-Ping Huang* (2005). Simple sequence repeat-based consensus linkage map of Bombyx mori. Proc. Natl. Acad. Sci. USA 102: 16305-16308

7. Shuang-Xi Ren, et al., Guo-Ping Zhao* (2003). Unique Physiological and Pathogenic Features of Leptospira interrogans Revealed by Whole Genome Sequencing. Nature 422: 888-893

8. QIAN, Wei, et al., Guoping Zhao*, Jiliang Tang*, Chaozu He* (2005) Comparative and Functional Genomic Analyses of the Pathogenicity of Phytopathogen Xanthomonas campestris pv. campestris. Genome Res 15(6): 757-767

9. The Chinese SARS molecular epidemiology consortium (2004). Molecular Evolution of the SARS Coronavirus During the Course of the SARS Epidemic in China. Science 303: 1666-1669 (*Correspondent of the whole work)

10. Huai-Dong Song, et al., Guo-Ping Zhao* (2005). Cross-host evolution of SARS coronavirus in palm civet and human Proc. Natl. Acad. Sci. USA 102: 2430-2435

11. Zheng H, et al., Zhao G*, Zhang Y.* (2008) Genetic basis of virulence attenuation revealed by comparative genomic analysis of Mycobacterium tuberculosis strain H37Ra versus H37Rv. PLoS ONE. 3(6): e2375.

12. Zhao W, et al., Wang S*, Ding X*, Zhao GP* (2010) Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism. Cell Res. 20: 1096–1108

13. The Schistosoma japonicum Genome Sequencing and Functional Analysis Consortium (2009) The Schistosoma japonicum genome reveals features of host–parasite interplay. Nature 460: 345-351

14. Qijun Wang, et al., Shimin Zhao*, Guo-Ping Zhao* (2010) Acetylation of Metabolic Enzymes Coordinates Carbon Source Utilization and Metabolic Flux. Science 327: 1004-1007

15. Lu LD, Sun Q, Fan XY, Zhong Y, Yao YF*, Zhao GP* (2010) Mycobacterial MazG is a novel NTP pyrophosphohydrolase involved in oxidative stress response. J Biol Chem. 285(36): 28076-85

16. Min Li, et al., Guoping Zhao*, Jeremy K. Nicholson*, Lanjuan Li*, and Liping Zhao* (2008) Symbiotic gut microbes modulate human metabolic phenotypes. Proc. Natl. Acad. Sci. USA. 105: 2117-2122